Antwerp University Hospital

In this randomized trial, we aim to evaluate the effect of novel conduction system pacing (CSP) versus conventional right ventricular apical pacing on exercise capacity in patients with heart failure (HF) and concomitant conduction system disorders. We hypothesize that CSP improves exercise capacity measured by peak oxygen uptake (VO2peak) as well as other markers of HF severity. The project will also provide deeper physiological insight into the mechanisms of VO2peak improvement by CSP.