KU Leuven
Using tissue samples from explanted lungs at the time of lung transplantation, we want to study the interaction between infection, inflammation, airway obstruction and remodeling and its impact on the
2023
Leuven
Project of Mieke Boon supported by the Fund A & J Forton and the Belgian CF Association, muco.be : 'Using tissue samples from explanted lungs at the time of lung transplantation, we want to study the interaction between infection, inflammation, airway obstruction and remodeling and its impact on the accompanying blood vessels in a detailed way. We want to use complementary techniques, mainly bulk RNA sequencing to identify up- or downregulated pathways, microbiome analysis, MILAN, spatial proteomics and single nuclear RNA sequencing to study these interactions'