KU Leuven
Airway in a dish: advancing translational testing of cystic fibrosis rescue strategies
2023
Leuven
Project van Marianne Carlon ondersteund door het Fonds A & J Forton en muco.be : 'The overall goal is to create cutting-edge cellular models mimicking CF airway pathology by: (1) creating a biobank of airway cells from patients and assess the effect of drugs on CFTR in a ‘personalized medicine’ approach, (2) improve airway cell models to evaluate the efficacy of gene-directed therapies better, (3) create an 'airway on multi-electrode array chip', to assess biological effects of CF and of CFTR-directed therapies at the level of individual cells composing the airways'(2) improve airway cell models to evaluate the efficacy of gene-directed therapies better, (3) create an 'airway on multi-electrode array chip', to assess biological effects of CF and of CFTR-directed therapies at the level of individual cells composing the airways'