Grantees

De Duve Institute

CD8+ T lymphocytes as mediators and markers of kidney disease progression in lupus nephritis (LN)

Project lead by Nisha Limaye : Lupus nephritis (LN) is a frequent complication of systemic lupus erythematosus (SLE): A complex autoimmune disorder that mainly affects young wome…

Hasselt University

Anti-UH-RA antibody reactivity for prediction of response to first-line therapy in rheumatoid arthritis: validation in the independent CAP48 cohort

Supported project of Patrick Van Dormael : Recently, baseline antibodies against 3 University Hasselt (UH)-RA antigens were found to be predictive for failure to achieve response…

Katholieke Universiteit Leuven

Comparative Impact of Reconstruction Surgery versus Conservative Treatment on early Cartilage Degeneration Following Anterior Cruciate Ligament Injury: Profiling Knee Joint Loading and Biomarkers

Project lead by Sabine Verschueren : Up to 50% of all ACL patients develop post-traumatic osteoarthritis (PTOA) 10 years after injury. Inflammatory responses due to injury and su…

KU Leuven (RA Clinical Research Group, Skeletal Biology and Engineering Research Centre, Department of Development and Regeneration, KU Leuven)

What is the optimal tapering strategy for rituximab in patients with Rheumatoid Arthritis: comparison of interval prolongation with disease activity guided dose reduction

Supported project of Patrick Verschueren : Rituximab is an effective drug, but it is expensive and might be accompanied by an increased infection risk. Therefore, lowering the do…

UZ Leuven

What is the optimal tapering strategy for rituximab in patients with Rheumatoid Arthritis: comparison of interval prolongation with disease activity guided dose reduction

Project lead by Patrick Verschueren - KU Leuven : 'What is the optimal tapering strategy for rituximab in patients with Rheumatoid Arthritis: comparison of interval prolongation …

Ghent University and Hospital

Risk stratification for spondyloarthritis development in inflammatory bowel disease: the REUvolution concept

Supported project lead by Gaëlle Varkas : I will investigate which patient profiles with new onset IBD are at higher risk for the development of respectively IBD or SpA. In the …

Katholieke Universiteit Leuven

Closing the seronegative gap in rheumatoid arthritis diagnosis using B-cell receptor sequencing combined with mass spectrometric analysis of complementarity determining regions.

Project lead by Jonas De Leeuw : In rheumatoid arthritis (RA), 1/3 patients is negative for RA-related biomarkers. We recently optimized an IgG-based mass spectrometric assay in …

Gent University

PRIOR-M: Predicting treatment Response In spOndyloarthRitis using gut Microbiome

Supported project of Dirk Elewaut and Emilie Dumas : The gut-joint axis is a key concept in our current understanding of spondyloarthritis. Considering the emerging role of gut d…

Gent University

SPIDER: Spondyloarthritis Precursors In first DEgree Relatives. Identifying gut microbiome alterations and early signs of subclinical gut inflammation in family members of spondyloarthritis patients.

Supported project: SPIDER: Spondyloarthritis Precursors In first DEgree Relatives. Identifying gut microbiome alterations and early signs of subclinical gut inflammation in famil…

UGent - Ghent University

Artificial intelligence for early detection of spondyloarthritis in medical imaging: development and validation of novel CT and MRI use cases for clinical practice.

Supported project of Jans Lennart : This project entails the further data collection for clinical validation studies of an MRI and CT use case for early detection of spondyloarth…

Université Catholique de Louvain - CIRTES

Transcriptome study of individual cells isolated from synovial biopsies: can it help in the therapeutic management of early rheumatoid arthritis ?

Supported project of Patrick Durez : Early diagnosis and therapeutic management of Rheumatoid arthritis (RA) are crucial. Early RA is treated with methotrexate (MTX) and after 3 …

UZ Gent

The prevalence of spondyloarthritis-like structural lesions of the sacroiliac joints on MRI in postpartum women.

Supported project of Filip Van den Bosch : A former study in 35 healthy postpartum women showed prevalence of sacroiliac bone marrow edema (BME) on magnetic resonance (MRI), rese…

UZ Leuven/ KU Leuven

Clinical field tests as predictors of cardiorespiratory fitness and cardiometabolic risk in Psoriatic Arthritis.

Supported project of Barbara Neerinckx : This project will study the potential of low cost, objective and highly generalisable clinical field tests, six minute walk and hand grip…

Gent University

Identifying a unique molecular cell profile on synovial biopsies in erosive hand osteoarthritis patients: a proof of concept (IMRPESSION study)

Support to the research project: 'Identifying a unique molecular cell profile on synovial biopsies in erosive hand osteoarthritis patients: a proof of concept (IMRPESSION study)'…

Ghent University and Hospital

Comparing axial radiographic damage and mobility of the spine in psoriatic arthritis (PsA) with newly diagnosed spondyloarthritis (SpA).

Soutien au projet de recherche : 'Comparing axial radiographic damage and mobility of the spine in psoriatic arthritis (PsA) with newly diagnosed spondyloarthritis (SpA)'.

Ghent University and Hospital

Strength, stretching and assistive devices, a multidisciplinary approach for patients with rheumatoid arthritis and hand involvement.

Support to the research project: 'Strength, stretching and assistive devices, a multidisciplinary approach for patients with rheumatoid arthritis and hand involvement'

KU Leuven

Single Cell Technologies Applied To Healthy Articular Cartilage Profiling

Support to the research project: 'Single Cell Technologies Applied To Healthy Articular Cartilage Profiling'

KU Leuven

Exploring PhysIcal therapy Care in Psoriatic Arthritis (EPIC-PsA trial)

Supported project : Exploring PhysIcal therapy Care in Psoriatic Arthritis (EPIC-PsA trial)

KU Leuven

A Reproductive Life Plan for women with Systemic Lupus Erythematosus: development and evaluation of user experiences

Support to the research project : 'A Reproductive Life Plan for women with Systemic Lupus Erythematosus: development and evaluation of user experiences'

CHU de Liège

Multimodal study of glucocorticoid-induced osteoporosis and myopathy: evaluation of bone and muscle toxicity by MRI, serum analysis and architecture measurement after different doses of glucocorticoid therapy initiation.

Soutien au projet de recherche : 'Multimodal study of glucocorticoid-induced osteoporosis and myopathy: evaluation of bone and muscle toxicity by MRI, serum analysis and architec…

Hasselt University

Elucidating the role of double homeobox protein 4 (DUX4) in the pathology of inflammatory arthritis

Soutien au projet de recherche : 'Elucidating the role of double homeobox protein 4 (DUX4) in the pathology of inflammatory arthritis'.

Katholieke Universiteit Leuven

Systemic sclerosis and occupational silica or solvent exposure: investigating epidemiology, gene-environment interactions and objective markers of exposure to improve occupational epidemiology, risk assessment and prevention.

Soutien au projet de recherche : 'Systemic sclerosis and occupational silica or solvent exposure: investigating epidemiology, gene-environment interactions and objective markers …

KU Leuven

How can we optimise the treatment with rituximab for patients with Rheumatoid Arthritis in daily clinical practice?

Soutien au projet de recherche : 'How can we optimise the treatment with rituximab for patients with Rheumatoid Arthritis in daily clinical practice?'.