Université Libre de Bruxelles
Rescuing mutant CFTR by delivering stabilizing nanobodies
2023
Ixelles
Projet de Cédric Govaerts soutenu par le Fonds A & J Forton et muco.be : 'We have developed stabilizing CFTR-nanobodies that can help rescue expression and function of mutant CFTR in synergy with currently approved correctors. They thus offer a route for improving current drugs or potentially treat mutations that are not eligible to these correctors. Our project aims at formulating nanobodies in a therapeutically compatible form using mRNA technology and lipid nanoparticles formulation'